Epicutis® Hydrobiome Serum

The EPICUTIS® Hydrobiome Serum is an EWG Verified (pending) formulation designed to improve overall skin health through balancing the microbiome and strengthening the skin barrier. This advanced formula combines two clinically proven actives — TCP, a patented, TLR2 modulator developed by Signum Biosciences that calms irritation and targets C. acnes and TPNa, a next-generation, form of water-soluble Vitamin E chosen for its antioxidant protection and ability to strengthen the skin barrier.

TCP works harmoniously within the skin’s microbiome, helping to calm visible irritation while supporting the balance of beneficial flora essential for healthy skin. Combined with TPNa's skin-barrier-strengthening properties, this formulation is ideal for addressing barrier damage or for general maintenance. These ingredients soothe discomfort, promote microbiome equilibrium, and reinforce the skin barrier for visibly clearer, calmer, and more resilient skin.

Lightweight and fast-absorbing, the Hydrobiome Serum delivers a refined, soothing experience that nurtures long-term skin health and microbiome balance.

Balancing, Calming + Strengthening Ingredients: 

• TCP to balance the microbiome + calm inflammation
• TPNa provides anti-oxidant protection
• Sodium Hyaluronate to instantly boost skin's moisture level
• Propanediol for skin plumping + anti-microbial benefits

Size: 50 ml / 1.7 fl oz

Apply two pumps of serum to clean fingertips. Gently spread it evenly over your face until it is fully absorbed. For your neck and décolleté, use an additional pump. For optimal results, use morning and night.

Water, Propanediol, Pentylene Glycol, Glycerin, Disodium Tetramethylhexadecenylcysteine Formylprolinate, Sodium Tocopheryl Phosphate, Sodium Hyaluronate, Sodium Phytate, Carbomer, Potassium Hydroxid